SCHEMBL7970133

SCHEMBL7970133

Nc1ccc2c(-c3ccccc3S(=O)(=O)O)c3ccc(=O)cc-3oc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 5/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
POLB P06746 3/20 0.50
ATM Q13315 2/20 0.50
PLEC Q15149 1/20 0.50
ABCB1 P08183 1/20 0.48
CFTR P13569 1/20 0.47
PAX8 Q06710 1/20 0.47
GOPC Q9HD26 1/20 0.47
ALPL P05186 2/20 0.46
NFKB1 P19838 2/20 0.46
NSD2 O96028 2/20 0.46
PLCG1 P19174 2/20 0.46
KDM4A O75164 1/20 0.46
TNNI3 P19429 1/20 0.46
TNNT2 P45379 1/20 0.46
MMP14 P50281 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045870 0.87 USP2 (0.67) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL17088308 0.87 MEN1 (0.49) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL13045901 0.87 ABCB1 (0.49) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL7973529 0.85 USP2 (0.59) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL20256014 0.81 USP2 (0.55) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL3430200 0.81 USP2 (0.74) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL13045911 0.76 USP2 (0.48) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL19564789 0.74 USP2 (0.58) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL15865562 0.74 ABCB1 (0.50) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL15357420 0.74 ABCB1 (0.47) USP2L3MBTL1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed