Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045911 | 0.89 | USP2 (0.48) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL7970133 | 0.87 | USP2 (0.54) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL15355561 | 0.86 | USP2 (0.38) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL3744889 | 0.86 | ABCB1 (0.39) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL3744887 | 0.86 | ABCB1 (0.39) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13045840 | 0.86 | ABCB1 (0.39) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13045887 | 0.85 | ALDH1A1 (0.44) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL19143845 | 0.80 | KMT2A (0.49) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL24226774 | 0.77 | GNG2 (0.38) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL17936619 | 0.77 | USP2 (0.37) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9389183-B2 | Fluorogenic hydrazine-substituted compounds | Life Technologies Corporation (US) | 2016-07-12 | — | — | US | disclosed |
| US-8772487-B2 | Fluorogenic hydrazine-substituted compounds | Life Technologies Corporation (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130288911-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation | 2013-10-31 | — | — | US | disclosed |
| US-20100291547-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291547-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | ALDH2, ALDH1A2, HLCS | ABCB1 3051/4885USP2 3504/4885ATM 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.