Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690689 | 0.82 | PTPN2 (0.43) | PTPN2PTPN1PTPN6TRPV1ABL1 | |
| SCHEMBL5690922 | 0.81 | PTPN2 (0.43) | PTPN2PTPN1PTPN6TRPV1ABL1 | |
| SCHEMBL5692100 | 0.79 | PTPN2 (0.44) | PTPN2PTPN1PTPN6TRPV1ABL1 | |
| SCHEMBL5691009 | 0.79 | MAPT (0.40) | TRPV1ALDH1A1GAAKMT2ALMNA | |
| SCHEMBL5690869 | 0.78 | POLB (0.43) | NPC1KMT2AMEN1 | |
| SCHEMBL5690361 | 0.78 | ENPP3 (0.39) | TRPV1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL5690759 | 0.77 | TRPV1 (0.41) | TRPV1ALDH1A1GAAKMT2ALMNA | |
| SCHEMBL5690856 | 0.76 | ENPP3 (0.35) | TRPV1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL5852341 | 0.76 | PTPN2 (0.48) | PTPN2PTPN1PTPN6TRPV1ABL1 | |
| SCHEMBL5690356 | 0.74 | ENPP2 (0.48) | TRPV1ALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291453-B1 | 4-amino-phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4 | ATHENA NEUROSCIENCES, INC. | 2001-09-18 | — | — | US | disclosed |