Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690403 | 0.95 | ENPP2 (0.47) | ENPP2NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5690361 | 0.75 | ENPP3 (0.39) | ENPP2SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL7970301 | 0.74 | PTPN2 (0.44) | NPC1RAB9ALMNAMAPTTRPV1 | |
| SCHEMBL5690604 | 0.74 | ENPP2 (0.48) | ENPP2NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5690337 | 0.72 | ENPP2 (0.49) | ENPP2NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5691009 | 0.72 | MAPT (0.40) | ENPP2SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL5691183 | 0.72 | ITGB1 (0.60) | ENPP2ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL5690873 | 0.72 | ITGB1 (0.60) | ENPP2ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL5690759 | 0.72 | TRPV1 (0.41) | ENPP2SMN1; SMN2HTTLMNAMAPT | |
| Hydrochloric Acid SCHEMBL5681091 | 0.71 | ENPP2 (0.66) | ENPP2NPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | disclosed |