Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970570 | 0.92 | KAT2B (0.71) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL8985656 | 0.88 | KAT2B (0.64) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL1594797 | 0.85 | ALDH1A1 (0.72) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL17678391 | 0.84 | ALDH1A1 (0.71) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL9759799 | 0.84 | ALDH1A1 (0.71) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL7746062 | 0.84 | ALDH1A1 (0.71) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL10249409 | 0.83 | KAT2B (0.71) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL29959799 | 0.82 | ALDH1A1 (0.63) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A | |
| SCHEMBL29377506 | 0.82 | KAT2B (0.69) | ALDH1A1KAT2BSMN1; SMN2KMT2AMAPT | |
| SCHEMBL14335786 | 0.82 | ALDH1A1 (0.63) | ALDH1A1NPSR1KAT2BSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |