Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509893 | 0.86 | NPC1 (0.65) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL693305 | 0.84 | NPC1 (0.67) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| Fluoride SCHEMBL27705811 | 0.82 | NPC1 (0.65) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| Hydrochloric Acid SCHEMBL28063043 | 0.82 | NPC1 (0.65) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL1990363 | 0.82 | NPC1 (0.69) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL295136 | 0.82 | NPC1 (0.69) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL28809154 | 0.81 | MAOB (0.49) | NPC1RAB9AEPHX2PARP10ALDH1A1 | |
| SCHEMBL28782576 | 0.81 | NPC1 (0.59) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL28808717 | 0.81 | IDO1 (0.47) | NPC1RAB9AEPHX2 | |
| SCHEMBL771707 | 0.80 | NPC1 (0.57) | NPC1RAB9AEPHX2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-218620662-U | Production device of propyzamide | 成武县晨晖环保科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-112079747-B | N-benzyloxy substituted symmetrical oxamide compound and preparation method and application thereof | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112079747-A | N-benzyloxy substituted symmetrical oxamide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-15 | — | — | CN | disclosed |
| US-6262040-B1 | Indazole derivatives and their use as inhibitors of phosphodiesterase (PDE) type IV and the production of tumor necrosis factor (TNF) | PFIZER INC | 2001-07-17 | — | — | US | disclosed |