SCHEMBL771707

SCHEMBL771707

C=C(C)C(=O)NOCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.57
RAB9A P51151 7/20 0.57
EPHX2 P34913 2/20 0.51
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
BRD4 O60885 1/20 0.43
HDAC3 O15379 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27606124 0.90 NPC1 (0.54) NPC1RAB9AEPHX2ALDH1A1KDM4E
SCHEMBL6509893 0.82 NPC1 (0.65) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL680273 0.82 NPC1 (0.65) NPC1RAB9AEPHX2ALDH1A1BRD4
SCHEMBL7151183 0.81 NPC1 (0.56) NPC1RAB9AEPHX2ALDH1A1
SCHEMBL13314114 0.81 NPC1 (0.59) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL7970706 0.80 NPC1 (0.62) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL873416 0.78 NPC1 (0.65) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL1990363 0.77 NPC1 (0.69) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL295136 0.77 NPC1 (0.69) NPC1RAB9AEPHX2ALDH1A1HDAC3
SCHEMBL28782576 0.77 NPC1 (0.59) NPC1RAB9AEPHX2ALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1440101-B1 POLYURETHANE, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2007-01-31 EP claimed
EP-1311628-B1 PSEUDOPLASTIC POWDERED LACQUER SLURRY FREE OF ORGANIC SOLVENTS AND EXTERNAL EMULSIFIERS, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2006-10-25 EP claimed
EP-1311580-B1 SINGLE COMPONENT SYSTEM SETTING BY THERMAL MEANS OR BY ACTINIC IRRADIATION AND USE THEREOF BASF COATINGS AG (DE) 2006-06-28 EP claimed
US-6930155-B2 Powder coatings based on thermoset-modified polymers and polyesters DEGUSSA AG (DE) 2005-08-16 US claimed
EP-1127905-B1 Transparent or pigmented powder coatings with crosslinkers from hydroxyalkylamides and blocked non-aromatic polyisocyanates DEGUSSA (DE) 2005-03-09 EP claimed
US-20040014881-A1 Single component system setting thermal means or by actinic irradiation and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-01-22 US claimed
US-20030212205-A1 Powder coatings based on thermoset-modified polymers and polyesters DEGUSSA AG (DE) 2003-11-13 US claimed
US-20030144413-A1 Pseudoplastic powdered lacquer slurry free of organic solvent and external emulsifiers, method for production and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2003-07-31 US claimed
US-20030104217-A1 Polyurethane powder coating compositions DEGUSSA AG (DE) 2003-06-05 US claimed
US-6500548-B2 POWDER COATING DEGUSSA AG (DE) 2002-12-31 US claimed
US-20010021748-A1 Transparent or pigmented powder coating materials with crosslinkers comprising hydroxyalkylamides and blocked nonaromatic polyisocyanates DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2001-09-13 US claimed
US-12509593-B2 Bismuth containing electrocoating material with improved catalytic activity BASF COATINGS GMBH (DE) 2025-12-30 US disclosed
US-12460093-B2 Aqueous electrocoating materials comprising a silane-containing crosslinker BASF COATINGS GMBH (DE) 2025-11-04 US disclosed
EP-4615896-A1 SCRATCH RESISTANT ONE-PACK COATING MATERIAL BASF Coatings GmbH (DE) 2025-09-17 EP disclosed
EP-3921589-B1 BALLISTIC-RESISTANT COMPOSITE WITH BLOCKED ISOCYANATE BARRDAY CORP (US) 2025-07-09 EP disclosed
US-4668360-A Process for electrocoating water reducible quaternary ammonium salt containing polymers THE SHERWIN-WILLIAMS COMPANY (US) 1987-05-26 US disclosed
US-4561952-A Water reducible quaternary ammonium salt containing polymers THE SHERWIN-WILLIAMS COMPANY (US) 1985-12-31 US disclosed
US-4444955-A Water reducible quaternary ammonium salt containing polymers THE SHERWIN-WILLIAMS COMPANY (US) 1984-04-24 US disclosed
US-4444954-A WITH ACTIVE HYDROGEN-CONTAINING MONOMER AND A BLOCKED POLYISOCYANATE THE SHERWIN-WILLIAMS COMPANY (US) 1984-04-24 US disclosed
US-4008192-A Polyisocyanates blocked with hydroxamic acid esters or acyl hydroxamates AKZO N.V. (NL) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509593-B2 Bismuth containing electrocoating material with improved catalytic activity EPX, COL1A1, COL2A1 NPC1 4739/4885RAB9A 2942/4885EPHX2 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.