Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839962 | 0.82 | LMNA (0.44) | MMP13MMP2 | |
| SCHEMBL7831749 | 0.77 | GPR119 (0.47) | GPR119 | |
| SCHEMBL7832576 | 0.76 | GPR119 (0.48) | GPR119 | |
| Hydrochloric Acid SCHEMBL7977476 | 0.75 | HTR6 (0.40) | — | |
| SCHEMBL21626630 | 0.74 | GPR119 (0.60) | GPR119STSTGFBR1MMP13 | |
| SCHEMBL7839249 | 0.74 | GPR119 (0.46) | GPR119 | |
| SCHEMBL7831565 | 0.72 | GPR119 (0.54) | GPR119 | |
| SCHEMBL7838633 | 0.72 | GPR119 (0.48) | GPR119 | |
| SCHEMBL1498322 | 0.72 | STS (0.50) | GPR119STSTGFBR1RORC | |
| SCHEMBL31382005 | 0.71 | GPR119 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248756-B1 | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |
| US-5891889-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-04-06 | — | — | US | disclosed |