Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 2/20 | 0.42 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.42 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLR1A | O95602 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616203 | 0.89 | KMT2A (0.40) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL3431068 | 0.89 | KMT2A (0.40) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL8140198 | 0.85 | DRD3 (0.44) | — | |
| SCHEMBL19009679 | 0.82 | ALDH1A1 (0.44) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL7965189 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL3940873 | 0.81 | ACKR3 (0.43) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL19000005 | 0.78 | ACKR3 (0.41) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL19652207 | 0.78 | ACKR3 (0.41) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL26343464 | 0.78 | ACKR3 (0.53) | ACKR3CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL3068209 | 0.78 | L3MBTL3 (0.56) | CDYLCDY1; CDY1BALDH1A1L3MBTL3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1044971-A1 | TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-10-18 | — | — | EP | disclosed |