Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968421 | 0.91 | CPA1 (0.40) | CPA1CPB2CPB1 | |
| SCHEMBL7971636 | 0.91 | CPA1 (0.38) | CPA1CPB2CPB1BRS3ADRA2A | |
| SCHEMBL7971115 | 0.83 | CPA1 (0.36) | CPA1CPB2CPB1NLN | |
| SCHEMBL7967524 | 0.83 | CPA1 (0.37) | CPA1CPB2CPB1TSHRNLN | |
| SCHEMBL7974145 | 0.76 | CPA1 (0.36) | CPA1CPB2CPB1BRS3 | |
| SCHEMBL7971730 | 0.74 | CPA1 (0.37) | CPA1CPB2CPB1BRS3 | |
| SCHEMBL7971542 | 0.74 | CPA1 (0.39) | CPA1CPB2CPB1LMNAMAPT | |
| SCHEMBL7971101 | 0.69 | FNTA (0.48) | TSHRPTGIR | |
| SCHEMBL7958574 | 0.67 | TSHR (0.39) | TSHRDRD2DRD4LMNAMAPT | |
| SCHEMBL7973949 | 0.67 | FTO (0.42) | CPA1CPB2CPB1NLNS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |