Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958183 | 0.91 | CPA1 (0.46) | FTOCPA1LMNAKDM4EALDH1A1 | |
| SCHEMBL7969211 | 0.90 | CPA1 (0.42) | FTOCPA1PPARGLMNAKDM4E | |
| SCHEMBL7973958 | 0.67 | LMNA (0.38) | LMNANLNMEN1KMT2AKDM5A | |
| SCHEMBL7971080 | 0.67 | TAAR1 (0.47) | — | |
| SCHEMBL7967524 | 0.66 | CPA1 (0.37) | FTOCPA1LMNANLNMEN1 | |
| SCHEMBL7971115 | 0.65 | CPA1 (0.36) | CPA1NLNCPB2CPB1 | |
| SCHEMBL9251459 | 0.65 | ALDH1A1 (0.59) | LMNAKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1549210 | 0.64 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ACXCR2 | |
| SCHEMBL9147199 | 0.64 | TRPV1 (0.55) | LMNAKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6722933 | 0.62 | APEX1 (0.64) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |