Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967524 | 0.91 | CPA1 (0.37) | CPA1CPB2HIF1AKMT2ACPB1 | |
| SCHEMBL7971542 | 0.91 | CPA1 (0.39) | CPA1CPB2HIF1AALDH1A1KMT2A | |
| SCHEMBL7971636 | 0.83 | CPA1 (0.38) | CPA1CPB2TP53CYP19A1CPB1 | |
| SCHEMBL7974145 | 0.78 | CPA1 (0.36) | CPA1CPB2CYP19A1CPB1BRS3 | |
| SCHEMBL7968421 | 0.74 | CPA1 (0.40) | CPA1CPB2ALDH1A1CPB1 | |
| SCHEMBL7971099 | 0.74 | CPA1 (0.38) | CPA1CPB2CPB1BRS3 | |
| SCHEMBL7971115 | 0.71 | CPA1 (0.36) | CPA1CPB2CPB1 | |
| SCHEMBL7972160 | 0.70 | ITGA4 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL7971733 | 0.69 | KMT2A (0.41) | TP53POLBALDH1A1GAAKMT2A | |
| SCHEMBL7969211 | 0.66 | CPA1 (0.42) | CPA1CPB2ALDH1A1CYP19A1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |