Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 9/20 | 0.47 |
| ▸ | HEXB | P07686 | 9/20 | 0.47 |
| ▸ | OGA | O60502 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030552 | 0.93 | HEXA (0.41) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL8138820 | 0.80 | TERT (0.45) | HEXAHEXBTERTHTR1ADRD2 | |
| SCHEMBL8138008 | 0.80 | HEXA (0.58) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL7982341 | 0.77 | TERT (0.40) | TERTHTR1ADRD2HTR2A | |
| SCHEMBL8131231 | 0.77 | HEXA (0.48) | HEXAHEXBOGASIRT1TERT | |
| Bromide SCHEMBL7985004 | 0.76 | HEXA (0.47) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL8129190 | 0.75 | SIRT1 (0.63) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL7982362 | 0.74 | HEXA (0.51) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL8126116 | 0.74 | HEXA (0.54) | HEXAHEXBOGASIRT1TERT | |
| SCHEMBL8125966 | 0.72 | SIRT1 (0.49) | HEXAHEXBOGASIRT1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| EP-0820985-B1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-08-30 | — | — | EP | disclosed |