Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327363 | 0.92 | MMP2 (0.48) | ALDH1A1GAATDP1PSEN1PSEN2 | |
| SCHEMBL8319435 | 0.89 | MMP2 (0.48) | ACHEALDH1A1GAAATMHTT | |
| SCHEMBL3148192 | 0.88 | ACHE (0.50) | ACHEALDH1A1HTTLMNAEPHX2 | |
| SCHEMBL5310614 | 0.88 | PSEN1 (0.59) | ACHEALDH1A1HTTLMNATDP1 | |
| SCHEMBL8320723 | 0.85 | PSEN1 (0.43) | ACHEALDH1A1ATMHTTLMNA | |
| SCHEMBL2964063 | 0.85 | PSEN1 (0.43) | ACHEALDH1A1ATMHTTLMNA | |
| SCHEMBL8327403 | 0.85 | TDP1 (0.41) | ACHEALDH1A1GAAATMHTT | |
| SCHEMBL8320725 | 0.85 | EPHX2 (0.42) | ACHEALDH1A1ATMHTTLMNA | |
| SCHEMBL8320747 | 0.85 | TDP1 (0.41) | ACHEALDH1A1GAAATMHTT | |
| SCHEMBL2969395 | 0.85 | TDP1 (0.41) | ACHEALDH1A1GAAATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| CN-1260345-A | Hydrazide compound, its preparing method and medicine compositions thereof | ADIR ET COMPANGIE (FR) | 2000-07-19 | — | — | CN | disclosed |