Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6869748 | 0.98 | AXL (0.31) | AXLPRKCINOS3NOS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7995412 | 0.98 | AXL (0.31) | AXLPRKCINOS3NOS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3180486 | 0.98 | AXL (0.31) | AXLPRKCINOS3NOS2ALDH1A1 | |
| SCHEMBL30506625 | 0.81 | LOXL2 (0.39) | AXLPRKCINOS3NOS2ALDH1A1 | |
| SCHEMBL7984286 | 0.81 | ALDH1A1 (0.41) | AXLPRKCINOS3NOS2ALDH1A1 | |
| SCHEMBL30872392 | 0.81 | ALDH1A1 (0.41) | AXLPRKCINOS3NOS2ALDH1A1 | |
| SCHEMBL21355820 | 0.81 | LOXL2 (0.39) | AXLPRKCINOS3NOS2ALDH1A1 | |
| SCHEMBL10714692 | 0.80 | NOS2 (0.46) | NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL6868388 | 0.79 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7099724 | 0.79 | PDE3B (0.40) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102108077-B | Method for preparing dexlansoprazole | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-102134232-B | isotopically substituted proton pump inhibitors | NYCOMED GMBH | 2012-11-21 | — | — | CN | disclosed |
| CN-102399212-A | Dexlansoprazole crystal form and preparation method thereof | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2012-04-04 | — | — | CN | disclosed |
| CN-101268051-B | Isotopically substituted proton pump inhibitors | NYCOMED GMBH | 2011-08-31 | — | — | CN | disclosed |
| CN-102134232-A | Isotopically substituted proton pump inhibitors | ALTANA PHARMA AG | 2011-07-27 | — | — | CN | disclosed |
| CN-102108077-A | Method for preparing dexlansoprazole | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-102108076-A | Method for preparing amorphous dexlansoprazole | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-101268051-A | Isotopically substituted proton pump inhibitors | NYCOMED GMBH (DE) | 2008-09-17 | — | — | CN | disclosed |
| CN-1789251-A | Production method of prazole heterocyclic compound and salt thereof | JIANGSU HAOSEN PHARMACEUTICAL (CN) | 2006-06-21 | — | — | CN | disclosed |
| WO-2001004109-A1 | PROCESS FOR THE PRODUCTION OF 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES | QUIMICA SINTETICA, S.A. (ES) | 2001-01-18 | — | — | WO | disclosed |