Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872392 | 1.00 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1RECQLPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL6868388 | 0.98 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1RECQLPDE3BPDE3A | |
| SCHEMBL7971571 | 0.81 | AXL (0.31) | ALDH1A1AXLPRKCINOS3NOS2 | |
| Hydrochloric Acid SCHEMBL3180486 | 0.79 | AXL (0.31) | ALDH1A1AXLPRKCINOS3NOS2 | |
| SCHEMBL21355820 | 0.79 | LOXL2 (0.39) | ALDH1A1KDM4EKMT2AAXLPRKCI | |
| Hydrochloric Acid SCHEMBL6869748 | 0.79 | AXL (0.31) | ALDH1A1AXLPRKCINOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7995412 | 0.79 | AXL (0.31) | ALDH1A1AXLPRKCINOS3NOS2 | |
| SCHEMBL30506625 | 0.79 | LOXL2 (0.39) | ALDH1A1KDM4EKMT2AAXLPRKCI | |
| SCHEMBL2083503 | 0.78 | NOS2 (0.46) | ALDH1A1L3MBTL1RECQLPDE3BPDE3A | |
| SCHEMBL7012351 | 0.78 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1RECQLPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981671-B2 | Bicyclic pyrazolyl amines as CDK2 inhibitors | INCYTE CORPORATION (US) | 2024-05-14 | — | — | US | disclosed |
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | VERNALIS (R&D) LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| EP-4277892-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2023-11-22 | — | — | EP | disclosed |
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| WO-2023134713-A1 | FUSED AZAHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 南方科技大学 | 2023-07-20 | — | — | WO | disclosed |
| US-20230002376-A1 | BICYCLIC PYRAZOLYL AMINES AS CDK2 INHIBITORS | INCYTE CORPORATION | 2023-01-05 | — | — | US | disclosed |
| US-20230002376-A1 | BICYCLIC PYRAZOLYL AMINES AS CDK2 INHIBITORS | INCYTE CORPORATION | 2023-01-05 | — | — | US | disclosed |
| WO-2022152705-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2022-07-21 | — | — | WO | disclosed |
| US-20210363139-A1 | CXCR4 INHIBITORS AND USES THEREOF | X4 PHARMACEUTICALS, INC. | 2021-11-25 | — | — | US | disclosed |
| US-10988465-B2 | CXCR4 inhibitors and uses thereof | X4 PHARMACEUTICALS, INC. (US) | 2021-04-27 | — | — | US | disclosed |
| CN-102399212-A | Dexlansoprazole crystal form and preparation method thereof | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2012-04-04 | — | — | CN | disclosed |
| CN-102108076-A | Method for preparing amorphous dexlansoprazole | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-102108077-A | Method for preparing dexlansoprazole | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-1789251-A | Production method of prazole heterocyclic compound and salt thereof | JIANGSU HAOSEN PHARMACEUTICAL (CN) | 2006-06-21 | — | — | CN | disclosed |
| CN-1070488-C | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-09-05 | — | — | CN | disclosed |
| WO-2001004109-A1 | PROCESS FOR THE PRODUCTION OF 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES | QUIMICA SINTETICA, S.A. (ES) | 2001-01-18 | — | — | WO | disclosed |
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| CN-1159803-A | Substituted Arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEM FAB (DE) | 1997-09-17 | — | — | CN | disclosed |
| EP-0764161-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034554-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BAX, BCL2A1 | ALDH1A1 1439/4885L3MBTL1 2956/4885RECQL 836/4885 |
| US-20230002376-A1 | BICYCLIC PYRAZOLYL AMINES AS CDK2 INHIBITORS | CDK2, CCNI, CDK1 | ALDH1A1 2543/4885L3MBTL1 4615/4885RECQL 849/4885 |
| US-11981671-B2 | Bicyclic pyrazolyl amines as CDK2 inhibitors | CDK2, CCNI, CDK1 | ALDH1A1 2543/4885L3MBTL1 4615/4885RECQL 849/4885 |
| US-20210363139-A1 | CXCR4 INHIBITORS AND USES THEREOF | CXCR4, CXCL12, CXCR3 | ALDH1A1 1512/4885L3MBTL1 3322/4885RECQL 4421/4885 |
| US-10988465-B2 | CXCR4 inhibitors and uses thereof | CXCR4, CXCL12, CXCR3 | ALDH1A1 1512/4885L3MBTL1 3322/4885RECQL 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.