SCHEMBL7971709

SCHEMBL7971709

CCCCS(=O)(=O)c1cncc(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.37
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PNMT P11086 1/20 0.34
HCAR2 Q8TDS4 1/20 0.33
GSR P00390 1/20 0.33
TXNRD1 Q16881 1/20 0.33
CCR4 P51679 1/20 0.33
HTR6 P50406 1/20 0.33
ACLY P53396 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
PTGS2 P35354 1/20 0.33
NAMPT P43490 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969245 0.90 CYP2C9 (0.37) ALDH1A1CYP3A4CYP2C9CYP2C19HCAR2
SCHEMBL7971560 0.84 PSIP1 (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19HCAR2
SCHEMBL7974914 0.77 HCAR2 (0.38) HCAR2HTR6ACLYPTGS2NAMPT
SCHEMBL10631511 0.73 ALDH1A1 (0.46) THRBALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL12417957 0.72 PTGS2 (0.48) HCAR2ACLYPTGS2
SCHEMBL31097440 0.72 PTGS2 (0.48) HCAR2ACLYPTGS2
SCHEMBL29297465 0.71 L3MBTL1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19POLB
SCHEMBL1828079 0.70 HCAR2 (0.42) ALDH1A1CYP3A4HCAR2HTR6ACLY
SCHEMBL14426918 0.69 NPC1 (0.50) THRBALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL31490469 0.69 SMN1; SMN2 (0.41) HCAR2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed