Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958183 | 0.91 | CPA1 (0.46) | CPA1CXCR2CPB2FTOKDM4E | |
| SCHEMBL7973949 | 0.90 | FTO (0.42) | CPA1CXCR2CPB2FTOKDM4E | |
| SCHEMBL7971636 | 0.67 | CPA1 (0.38) | CPA1CPB2SMN1; SMN2CPB1CYP19A1 | |
| SCHEMBL7969216 | 0.67 | BRS3 (0.37) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7970889 | 0.67 | TAAR1 (0.47) | — | |
| SCHEMBL7971730 | 0.66 | CPA1 (0.37) | CPA1CPB2ALDH1A1CPB1CYP19A1 | |
| SCHEMBL7974145 | 0.66 | CPA1 (0.36) | CPA1CPB2CPB1CYP19A1BRS3 | |
| SCHEMBL9151220 | 0.64 | NPC1 (0.56) | KDM4EALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL9450042 | 0.62 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30127637 | 0.61 | NPC1 (0.56) | KDM4EALDH1A1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |