Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958651 | 0.84 | NFE2L2 (0.56) | NFE2L2RELANPC1RAB9ACYP1A2 | |
| SCHEMBL7971834 | 0.83 | TLR4 (0.42) | NFE2L2KMT2A | |
| SCHEMBL7970291 | 0.79 | TP53 (0.44) | NFE2L2RELANPC1RAB9AMEN1 | |
| SCHEMBL7969857 | 0.78 | NFE2L2 (0.49) | NFE2L2CHRM5RELAMEN1KMT2A | |
| SCHEMBL2099510 | 0.77 | CHRM5 (0.67) | NFE2L2CHRM5RELACYP19A1NQO2 | |
| SCHEMBL28825636 | 0.76 | NFE2L2 (0.55) | NFE2L2CHRM5RELANPC1RAB9A | |
| SCHEMBL18240600 | 0.75 | RELA (0.62) | NFE2L2CHRM5RELAMEN1KMT2A | |
| SCHEMBL18240779 | 0.73 | RELA (0.56) | NFE2L2CHRM5RELAMEN1KMT2A | |
| SCHEMBL3301399 | 0.72 | CHRM5 (0.60) | NFE2L2CHRM5RELAMEN1KMT2A | |
| SCHEMBL7974639 | 0.71 | CHRM5 (0.46) | NFE2L2CHRM5RELANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |