Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972007 | 0.83 | NFE2L2 (0.54) | NFE2L2KMT2A | |
| SCHEMBL7969857 | 0.77 | NFE2L2 (0.49) | MAPTSMN1; SMN2MAOBNFE2L2KMT2A | |
| SCHEMBL7970291 | 0.74 | TP53 (0.44) | LMNAMAPTALOX5SMN1; SMN2ALDH1A1 | |
| SCHEMBL7972130 | 0.72 | ALOX5 (0.44) | TLR4TLR2LMNAMAPTALOX5 | |
| SCHEMBL11230775 | 0.71 | TLR4 (0.53) | TLR4TLR2LMNAMAPTALOX5 | |
| SCHEMBL7958651 | 0.70 | NFE2L2 (0.56) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16608257 | 0.70 | GRM4 (0.61) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27900292 | 0.69 | TLR4 (0.64) | TLR4TLR2ALOX5PTGS1PTGS2 | |
| SCHEMBL4553033 | 0.69 | TLR4 (0.54) | TLR4TLR2LMNAMAPTALOX5 | |
| SCHEMBL4711271 | 0.69 | GRM4 (0.69) | TLR4TLR2LMNAMAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |