Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699063 | 0.88 | CHRNB2 (0.34) | CYP11B1CYP11B2RIPK2PDE4APDE4B | |
| SCHEMBL7230387 | 0.85 | KMT2A (0.40) | KMT2ACYP11B1CYP11B2SMN1; SMN2KDM4E | |
| SCHEMBL7972022 | 0.82 | RIPK2 (0.32) | RIPK2OPRL1 | |
| SCHEMBL7223598 | 0.82 | OPRL1 (0.36) | CYP11B1CYP11B2RIPK2CHRNB4CHRNA3 | |
| SCHEMBL7971900 | 0.77 | CHRNB2 (0.38) | KMT2ACYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL7661747 | 0.75 | KMT2A (0.34) | KMT2ACYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL7221029 | 0.73 | CHRNB2 (0.36) | CYP11B1CYP11B2PDE4APDE4BPDE4C | |
| SCHEMBL7986499 | 0.72 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL7697700 | 0.70 | GRM5 (0.41) | RIPK2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6573280 | 0.70 | SLC6A4 (0.37) | RIPK2CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294545-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1033914-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026478-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |