Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 3/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981738 | 0.84 | KDM4E (0.55) | NAMPTACKR3KDM4EPKM | |
| SCHEMBL7987532 | 0.84 | USP30 (0.39) | KDM4EUSP30 | |
| SCHEMBL7987167 | 0.80 | KDM4E (0.45) | NAMPTKDM4EPKMUSP30 | |
| Hydrochloric Acid SCHEMBL7981565 | 0.76 | HTR1A (0.43) | OPRD1 | |
| SCHEMBL7989896 | 0.75 | ACKR3 (0.49) | ACKR3 | |
| SCHEMBL8504314 | 0.74 | KDM1A (0.40) | METTL3KDM1AOPRD1PRMT5FPR3 | |
| Hydrochloric Acid SCHEMBL7986017 | 0.74 | IKBKB (0.45) | — | |
| SCHEMBL28153227 | 0.74 | KDM1A (0.50) | METTL3KDM1AOPRD1PRMT5FPR3 | |
| SCHEMBL6223221 | 0.73 | KDM4E (0.64) | METTL3KDM1AOPRD1PRMT5FPR3 | |
| SCHEMBL6223223 | 0.73 | KDM4E (0.64) | METTL3KDM1AOPRD1PRMT5FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |