Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985797 | 0.97 | ACKR3 (0.51) | ACKR3LMNATP53THRBSTAT3 | |
| SCHEMBL7989610 | 0.92 | ACKR3 (0.50) | ACKR3LMNATP53THRBMAPT | |
| SCHEMBL7984557 | 0.85 | ACKR3 (0.40) | ACKR3LMNATP53THRBSTAT3 | |
| SCHEMBL7981945 | 0.85 | KDM4E (0.44) | LMNATP53 | |
| SCHEMBL7987167 | 0.83 | KDM4E (0.45) | LMNATP53MAPT | |
| SCHEMBL7984736 | 0.82 | SMYD2 (0.46) | — | |
| SCHEMBL7984706 | 0.82 | DRD3 (0.42) | LMNATP53 | |
| SCHEMBL7987161 | 0.82 | SMYD2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL7971940 | 0.81 | SMYD2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7982703 | 0.81 | DRD3 (0.42) | LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |