Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981945 | 0.95 | KDM4E (0.44) | KDM4EPKMNAMPTGPR119LMNA | |
| SCHEMBL7981738 | 0.92 | KDM4E (0.55) | KDM4EPKMNAMPTLMNATP53 | |
| SCHEMBL7989610 | 0.87 | ACKR3 (0.50) | LMNATP53MAPT | |
| SCHEMBL7983268 | 0.84 | LIMK2 (0.47) | KDM4EPKMGPR119 | |
| SCHEMBL7989896 | 0.83 | ACKR3 (0.49) | LMNATP53MAPT | |
| SCHEMBL7983299 | 0.82 | NAMPT (0.39) | KDM4EPKMNAMPTGPR119LMNA | |
| Hydrochloric Acid SCHEMBL7983069 | 0.81 | ITGB3 (0.44) | NAMPTL3MBTL1 | |
| SCHEMBL7984557 | 0.81 | ACKR3 (0.40) | NAMPTLMNATP53MAPTL3MBTL1 | |
| SCHEMBL7989477 | 0.80 | KDM4E (0.47) | KDM4EPKMNAMPTGPR119TP53 | |
| SCHEMBL7989480 | 0.80 | KDM4E (0.47) | KDM4EPKMNAMPTGPR119TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |