Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007013 | 0.77 | AHR (0.45) | S100A4PTGS2TGM2CES1 | |
| SCHEMBL5007022 | 0.76 | TDO2 (0.43) | S100A4 | |
| SCHEMBL21744554 | 0.73 | MKNK1 (0.55) | MKNK1MKNK2FGFR1CYP11B1CYP11B2 | |
| SCHEMBL7232205 | 0.71 | METAP2 (0.49) | MKNK1MKNK2FGFR1CYP11B1CYP11B2 | |
| SCHEMBL30957059 | 0.69 | IDO1 (0.52) | MKNK1MKNK2FGFR1CYP11B1CYP11B2 | |
| SCHEMBL30345840 | 0.69 | IDO1 (0.52) | MKNK1MKNK2FGFR1CYP11B1CYP11B2 | |
| SCHEMBL29796762 | 0.69 | IDO1 (0.52) | MKNK1MKNK2FGFR1CYP11B1CYP11B2 | |
| Formaldehyde SCHEMBL28060910 | 0.69 | HCAR2 (0.52) | MKNK1MKNK2HCAR2 | |
| SCHEMBL5004411 | 0.68 | CNR1 (0.42) | CYP11B1CYP11B2S100A4PPARGCNR1 | |
| SCHEMBL27779502 | 0.68 | HPGD (0.47) | MKNK1MKNK2FGFR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |