Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972310 | 0.94 | PTGS2 (0.37) | PTGS2SLC6A3SLC6A4PKLRHTR7 | |
| SCHEMBL7959207 | 0.92 | ALDH1A1 (0.34) | SLC6A3SLC6A4PKLRSLC6A2ALDH1A1 | |
| SCHEMBL7929486 | 0.89 | ALDH1A1 (0.35) | PTGS2HTR7ALDH1A1HTT | |
| SCHEMBL7972724 | 0.87 | PTPN1 (0.36) | PTGS2SLC6A3SLC6A4PKLRSLC6A2 | |
| SCHEMBL7972213 | 0.84 | MAPT (0.34) | HPGDPOLBCA12CA9CTSL | |
| SCHEMBL7975087 | 0.83 | PTGS2 (0.37) | PTGS2HTR7ALDH1A1 | |
| SCHEMBL7928263 | 0.82 | F10 (0.34) | PTGS2SLC6A3SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL7929432 | 0.81 | PTGDR2 (0.32) | POLB | |
| SCHEMBL7972313 | 0.78 | HDAC1 (0.34) | HPGDPOLB | |
| SCHEMBL7934116 | 0.78 | CTSL (0.39) | ALDH1A1HSD17B10HPGDPOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |