Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953180 | 0.94 | CYP2C9 (0.62) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL9717851 | 0.90 | CYP2C9 (0.50) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL7972245 | 0.85 | ESR1 (0.54) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL14760247 | 0.83 | ALOX15 (0.54) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL30443132 | 0.81 | TSHR (0.78) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL2476258 | 0.81 | TSHR (0.58) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL297739 | 0.81 | TSHR (0.78) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL6232503 | 0.80 | TSHR (0.64) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL9006029 | 0.79 | TSHR (0.58) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 | |
| SCHEMBL28454013 | 0.79 | HSD17B10 (0.58) | TSHRCYP2C9HIF1AHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268462-B1 | Branched polycarbonate resin and process for the preparation thereof | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1008608-A1 | BRANCHED POLYCARBONATE RESIN AND PROCESS FOR THE PREPARATION THEREOF | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-4415725-A | MOLDING MATERIALS; BLOW MOLDING; BOTTLES; FILMS | GENERAL ELECTRIC CO. (US) | 1983-11-15 | — | — | US | disclosed |