Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985925 | 0.99 | HTR2A (0.41) | DRD2HTR2ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7989648 | 0.97 | SIGMAR1 (0.44) | DRD2HTR2ASIGMAR1DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL7972066 | 0.97 | SIGMAR1 (0.43) | DRD2HTR2ASIGMAR1DRD3HTR1A | |
| SCHEMBL7986609 | 0.88 | DRD3 (0.44) | ALDH1A1SMN1; SMN2DRD3 | |
| SCHEMBL7986288 | 0.88 | DRD3 (0.51) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL7985583 | 0.88 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7983890 | 0.87 | DRD3 (0.50) | DRD2HTR2ADRD3HTR1A | |
| Hydrochloric Acid SCHEMBL7981722 | 0.87 | DRD3 (0.44) | ALDH1A1SMN1; SMN2DRD3 | |
| Hydrochloric Acid SCHEMBL7983892 | 0.87 | ALDH1A1 (0.42) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984706 | 0.85 | DRD3 (0.42) | KDM4EALDH1A1SMN1; SMN2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |