Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 8/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972066 | 0.99 | SIGMAR1 (0.43) | SIGMAR1DRD3HTR2AHTR1ADRD2 | |
| SCHEMBL7972317 | 0.97 | DRD2 (0.42) | SIGMAR1DRD3HTR2AHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7985925 | 0.97 | HTR2A (0.41) | SIGMAR1DRD3HTR2AHTR1ADRD2 | |
| SCHEMBL7986218 | 0.88 | DRD3 (0.48) | DRD3HTR2AHTR1ADRD2DRD4 | |
| SCHEMBL7981746 | 0.88 | DRD3 (0.55) | DRD3HTR2AHTR1ADRD2HTR2C | |
| Hydrochloric Acid SCHEMBL7983764 | 0.87 | DRD3 (0.47) | DRD3HTR2AHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7989888 | 0.87 | DRD3 (0.54) | DRD3HTR2AHTR1ADRD2HTR2C | |
| SCHEMBL7986609 | 0.85 | DRD3 (0.44) | DRD3 | |
| SCHEMBL7985583 | 0.85 | ALDH1A1 (0.43) | SIGMAR1DRD4 | |
| SCHEMBL7986288 | 0.85 | DRD3 (0.51) | DRD3HTR2AHTR1ADRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |