Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931244 | 0.88 | MAPT (0.43) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL21950002 | 0.84 | MAPT (0.55) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL4017321 | 0.83 | MAPT (0.46) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL16082385 | 0.80 | SCN9A (0.45) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL8894557 | 0.77 | MAPT (0.47) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL17430831 | 0.77 | HRH3 (0.49) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL6849624 | 0.75 | PKM (0.49) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL27498274 | 0.75 | MAOB (0.56) | DAGLAABHD6KDM1AMAOAMAOB | |
| SCHEMBL669764 | 0.73 | MAPT (0.47) | MAPTPLCG2PKMNPC1RAB9A | |
| SCHEMBL3042985 | 0.73 | MAPT (0.47) | MAPTPLCG2PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |