Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.55 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.51 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260287 | 0.87 | CA2 (0.49) | MAPTPLCG2MALT1COXFA4GHSR | |
| SCHEMBL4972696 | 0.87 | CA2 (0.49) | MAPTPLCG2MALT1COXFA4GHSR | |
| SCHEMBL4017321 | 0.85 | MAPT (0.46) | MAPTPLCG2MALT1COXFA4GHSR | |
| SCHEMBL7972444 | 0.84 | MAPT (0.45) | MAPTPLCG2MALT1COXFA4GHSR | |
| SCHEMBL16082385 | 0.83 | SCN9A (0.45) | MAPTPLCG2COXFA4GHSRPKM | |
| SCHEMBL7931244 | 0.81 | MAPT (0.43) | MAPTPLCG2COXFA4GHSRPDE10A | |
| SCHEMBL8557528 | 0.80 | PKM (0.71) | MAPTPLCG2GHSRPKM | |
| SCHEMBL17430831 | 0.79 | HRH3 (0.49) | MAPTPLCG2COXFA4GHSRPDE10A | |
| SCHEMBL8558063 | 0.79 | CYP3A4 (0.57) | MAPTPLCG2GHSRKCNH2PKM | |
| SCHEMBL13005005 | 0.78 | HTR2A (0.63) | HTR2ADRD2HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643711-A1 | NEW ANTHELMINTIC COMPOUNDS | Bayer Animal Health GmbH (DE) | 2020-04-29 | — | — | EP | disclosed |