Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.52 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10882579 | 0.80 | NCF1 (0.46) | NCF1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7972118 | 0.76 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBPOLB | |
| SCHEMBL7971711 | 0.76 | MAPT (0.55) | PI4KAPI4K2BPI4K2API4KBPOLB | |
| SCHEMBL7985572 | 0.76 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBPOLB | |
| SCHEMBL11332805 | 0.76 | ALDH1A1 (0.50) | PI4KAPI4K2BPI4K2API4KBPOLB | |
| Quinolin-4-Amine SCHEMBL278276 | 0.74 | NCF1 (1.00) | NCF1PI4KAPI4K2BPI4K2API4KB | |
| Quinolin-4-Amine SCHEMBL29493365 | 0.74 | NCF1 (1.00) | NCF1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2790453 | 0.73 | PIK3CA (0.57) | PI4KAPI4K2BPI4K2API4KBPOLB | |
| Quinolin-4-Amine SCHEMBL27779896 | 0.73 | NCF1 (0.78) | NCF1POLBKMT2AALDH1A1GAA | |
| SCHEMBL10771544 | 0.73 | NR4A2 (0.45) | NCF1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140050778-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012092367-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2012-07-05 | — | — | WO | disclosed |
| US-6274596-B1 | MICROBIOCIDES FOR DRUG RESISTANCE INFECTIONS | ANADYS PHARMACEUTICALS, INC. | 2001-08-14 | — | — | US | disclosed |
| WO-2000024389-A2 | BENZOQUINOLINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-05-04 | — | — | WO | disclosed |
| US-6057287-A | KUNITZ DOMAIN HAVING DISULFIDE BONDS AT CYSTINE 5-55, 14-38, 30-51 POSITIONS | DYAX CORP. (US) | 2000-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140050778-A1 | NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF | NSUN3, NSUN2, HNRNPF | NCF1 736/4885PI4KA 4634/4885PI4K2B 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.