Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150595 | 0.77 | CYP3A4 (0.41) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL7971711 | 0.76 | MAPT (0.55) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL7972463 | 0.76 | NCF1 (0.59) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL11332805 | 0.76 | ALDH1A1 (0.50) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL7972118 | 0.76 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL244384 | 0.74 | NCF1 (0.56) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL29923695 | 0.74 | NCF1 (0.56) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL2170635 | 0.73 | PRKCI (0.38) | KMT2AHTTMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL2790453 | 0.73 | PIK3CA (0.57) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL1193688 | 0.73 | NQO2 (0.57) | PI4KAPI4K2BPI4K2API4KBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274596-B1 | MICROBIOCIDES FOR DRUG RESISTANCE INFECTIONS | ANADYS PHARMACEUTICALS, INC. | 2001-08-14 | — | — | US | disclosed |
| WO-2000024389-A2 | BENZOQUINOLINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-05-04 | — | — | WO | disclosed |