Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GPR132 | Q9UNW8 | 10/20 | 0.56 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.56 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976180 | 0.93 | GAA (0.57) | CYP3A4GAACYP2C19GPR132CMKLR2 | |
| SCHEMBL7973309 | 0.89 | TACR1 (0.65) | GPR132MEN1KMT2ATACR1GPR34 | |
| SCHEMBL8116271 | 0.85 | TACR1 (0.58) | CYP3A4GAACYP2C19GPR132CMKLR2 | |
| SCHEMBL7976251 | 0.82 | TACR1 (0.79) | KMT2ATACR1ECE1 | |
| SCHEMBL7971284 | 0.82 | GPR132 (0.56) | GPR132CMKLR2CMKLR1MEN1KMT2A | |
| SCHEMBL7969746 | 0.81 | HDAC8 (0.66) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL8121348 | 0.78 | USP30 (0.56) | CYP3A4GAACYP2C19GPR132KDM4E | |
| SCHEMBL7970040 | 0.78 | TACR1 (0.67) | CYP3A4MAPTKMT2ATACR1 | |
| SCHEMBL7973319 | 0.77 | HDAC8 (0.58) | MEN1KMT2AGPR34 | |
| SCHEMBL3562537 | 0.76 | HDAC8 (0.61) | MEN1KMT2AGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |