Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.51 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.51 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121348 | 0.88 | USP30 (0.56) | TACR1GAAKMT2AGPR132GRIA1 | |
| SCHEMBL7976251 | 0.88 | TACR1 (0.79) | TACR1ECE1LMNAKMT2ACTSL | |
| SCHEMBL8115805 | 0.87 | TACR1 (0.73) | TACR1KMT2ACTSLCTSBCTSS | |
| SCHEMBL7971284 | 0.85 | GPR132 (0.56) | TACR1ECE1LMNAMEN1NPC1 | |
| SCHEMBL7972845 | 0.85 | CYP3A4 (0.57) | TACR1ECE1GAAMEN1RAB9A | |
| SCHEMBL7415738 | 0.82 | ECE1 (0.64) | ECE1LMNACTRCMEN1NPC1 | |
| SCHEMBL27520437 | 0.82 | ECE1 (0.64) | ECE1LMNACTRCMEN1NPC1 | |
| SCHEMBL15869689 | 0.81 | ECE1 (0.62) | ECE1GAALMNACTRCMEN1 | |
| SCHEMBL7970040 | 0.81 | TACR1 (0.67) | TACR1KMT2ACTSLCTSBCTSS | |
| SCHEMBL30037998 | 0.81 | GPR132 (0.69) | ECE1LMNACTRCMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |