Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973309 | 0.91 | TACR1 (0.65) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7976180 | 0.91 | GAA (0.57) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8118400 | 0.87 | TACR1 (0.61) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7975877 | 0.86 | HDAC8 (0.63) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21422370 | 0.83 | HDAC8 (0.81) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7960080 | 0.82 | HDAC8 (0.56) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7971348 | 0.82 | TACR1 (0.83) | HDAC8ALDH1A1TACR1 | |
| SCHEMBL7972845 | 0.81 | CYP3A4 (0.57) | KMT2AGAAMEN1TACR1KDM4E | |
| SCHEMBL7976158 | 0.77 | MMP9 (0.58) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7971563 | 0.77 | KAT6A (0.53) | POLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |