Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972872 | 0.99 | L3MBTL1 (0.44) | L3MBTL1CCR2HTR4HTR2AKCNH2 | |
| SCHEMBL7972913 | 0.95 | LTA4H (0.42) | L3MBTL1CCR2HTR4KCNH2CACNA1I | |
| Hydrochloric Acid SCHEMBL7982374 | 0.94 | KDM1A (0.41) | L3MBTL1CCR2HTR4KCNH2CACNA1I | |
| SCHEMBL7981833 | 0.92 | HTR4 (0.47) | HTR4HTR2AKCNH2GSK3BFAAH | |
| SCHEMBL7985752 | 0.92 | CACNA1I (0.44) | HTR4HTR2AKCNH2CACNA1ILMNA | |
| SCHEMBL7982581 | 0.92 | CCR3 (0.46) | HTR4HTR2AKCNH2HTR7GSK3B | |
| Hydrochloric Acid SCHEMBL7986403 | 0.92 | HTR4 (0.47) | HTR4HTR2AKCNH2GSK3BFAAH | |
| Hydrochloric Acid SCHEMBL7984545 | 0.91 | CACNA1I (0.43) | HTR4HTR2AKCNH2CACNA1ILMNA | |
| Hydrochloric Acid SCHEMBL7983273 | 0.91 | CCR3 (0.45) | HTR4HTR2AKCNH2HTR7GSK3B | |
| SCHEMBL7986842 | 0.88 | HRH3 (0.44) | HTR4HTR7FAAHBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |