Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984545 | 0.99 | CACNA1I (0.43) | CACNA1IKCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL7981938 | 0.95 | CACNA1I (0.43) | CACNA1IKCNH2TP53MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7986131 | 0.94 | CACNA1I (0.42) | CACNA1IKCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL7972908 | 0.92 | L3MBTL1 (0.45) | CACNA1IKCNH2TP53HTR2AHTR4 | |
| Hydrochloric Acid SCHEMBL7972872 | 0.91 | L3MBTL1 (0.44) | CACNA1IKCNH2TP53HTR2AHTR4 | |
| SCHEMBL7981833 | 0.91 | HTR4 (0.47) | KCNH2HTR2AHTR4ACHEGSK3B | |
| SCHEMBL7982506 | 0.90 | HTR7 (0.41) | HTR2AHTR4ACHEGSK3BHTR7 | |
| Hydrochloric Acid SCHEMBL7986403 | 0.90 | HTR4 (0.47) | KCNH2HTR2AHTR4ACHEGSK3B | |
| Hydrochloric Acid SCHEMBL7983327 | 0.90 | HTR7 (0.41) | HTR2AHTR4ACHEGSK3BHTR7 | |
| SCHEMBL7972913 | 0.87 | LTA4H (0.42) | CACNA1IKCNH2HTR4HTR7CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |