Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15902409 | 0.81 | LOXL2 (0.67) | PDGFRBPDGFRACA2MTNR1AMTNR1B | |
| SCHEMBL6064390 | 0.78 | LOXL2 (0.44) | PDGFRBPDGFRACA2MTNR1AMTNR1B | |
| SCHEMBL6332064 | 0.76 | CA2 (0.62) | PDGFRBPDGFRAFGFR1CA2PDE3B | |
| SCHEMBL30880113 | 0.75 | LOXL2 (0.58) | PDGFRBPDGFRAFGFR1CA2MTNR1A | |
| SCHEMBL27195636 | 0.75 | LOXL2 (0.58) | PDGFRBPDGFRAFGFR1CA2MTNR1A | |
| SCHEMBL9516560 | 0.74 | PDGFRB (0.70) | PDGFRBPDGFRAFGFR1CA2XDH | |
| SCHEMBL7974481 | 0.73 | PPARG (0.55) | MEN1CYP2C9KMT2AKDM4EGAA | |
| SCHEMBL16756017 | 0.72 | LOXL2 (0.63) | PDGFRBPDGFRACA2MTNR1AMTNR1B | |
| SCHEMBL12870534 | 0.72 | LOXL2 (0.42) | XDHLOXL2MEN1CYP2C9TSHR | |
| SCHEMBL159833 | 0.72 | PTGS2 (0.55) | CYP2C9TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090105-A1 | ISOTHIAZOLES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |