Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12870534 | 0.83 | LOXL2 (0.42) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5974148 | 0.79 | PPARG (0.57) | PPARGALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL17316698 | 0.77 | ALDH1A1 (0.62) | PPARGALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28671523 | 0.74 | PPARG (0.61) | PPARGALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL7246369 | 0.74 | PPARG (0.61) | PPARGALDH1A1KDM4EMEN1MAPT | |
| Ibufenac SCHEMBL24244 | 0.74 | PTGS1 (0.60) | ALDH1A1HPGDHSD17B10PTGS1AKR1C3 | |
| SCHEMBL27724024 | 0.74 | KDM4E (0.55) | PPARGALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL7973131 | 0.73 | PDGFRB (0.56) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Ibufenac SCHEMBL503595 | 0.72 | PTGS1 (0.58) | ALDH1A1HPGDHSD17B10PTGS1AKR1C3 | |
| Ibufenac SCHEMBL11571262 | 0.72 | PTGS1 (0.58) | ALDH1A1HPGDHSD17B10PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090105-A1 | ISOTHIAZOLES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |