Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973511 | 0.84 | USP5 (0.45) | LMNAKDM4ECYP2C9USP5HTT | |
| SCHEMBL7990842 | 0.80 | CES2 (0.48) | LMNAKDM4ESMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL7987821 | 0.80 | USP5 (0.41) | LMNAKDM4ECYP2C9USP5HTT | |
| SCHEMBL7990738 | 0.78 | ALDH1A1 (0.50) | LMNAHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7990723 | 0.77 | KMT2A (0.58) | LMNAKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7987811 | 0.76 | CES2 (0.48) | CA1CA2CA9MAPTRAB9A | |
| SCHEMBL6316323 | 0.75 | CES2 (0.44) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL7973336 | 0.73 | ALDH1A1 (0.53) | LMNAHTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1148332 | 0.72 | CNR1 (0.58) | LMNAKDM4ECYP2C9USP5HTT | |
| SCHEMBL9420297 | 0.72 | CYP2C9 (0.57) | LMNAKDM4ECYP2C9USP5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |