Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987821 | 0.89 | USP5 (0.41) | USP5LMNAKDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL7973288 | 0.84 | LMNA (0.47) | USP5LMNAKDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL7984824 | 0.82 | HTT (0.46) | LMNAKDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7990725 | 0.80 | ALDH1A1 (0.45) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7984994 | 0.79 | KMT2A (0.53) | LMNAKDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7990882 | 0.79 | HTT (0.46) | KDM4EKMT2AALDH1A1HTTPOLB | |
| SCHEMBL7987064 | 0.79 | ALDH1A1 (0.52) | LMNASMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL6316440 | 0.78 | NPSR1 (0.55) | LMNAKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7984979 | 0.76 | HDAC1 (0.46) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7983730 | 0.76 | CES2 (0.50) | MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |