Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984994 | 0.85 | KMT2A (0.53) | KMT2APARP10PTGS2POLBGLA | |
| SCHEMBL7987850 | 0.82 | KMT2A (0.51) | KMT2APARP10ALDH1A1LMNANPC1 | |
| SCHEMBL7987818 | 0.82 | KMT2A (0.49) | KMT2APARP10PTGS2POLBGLA | |
| SCHEMBL7985090 | 0.80 | CES2 (0.55) | KMT2APARP10MAPTALDH1A1LMNA | |
| SCHEMBL14879107 | 0.79 | KMT2A (0.61) | KMT2APARP10POLBGLAMAPT | |
| SCHEMBL7973288 | 0.77 | LMNA (0.47) | KMT2APOLBMAPTALDH1A1LMNA | |
| SCHEMBL7990900 | 0.76 | PARP10 (0.56) | KMT2APARP10ALDH1A1NPC1RAB9A | |
| SCHEMBL2517350 | 0.75 | KMT2A (0.73) | KMT2APARP10POLBGLAMAPT | |
| SCHEMBL103890 | 0.74 | KMT2A (0.70) | KMT2APARP10POLBGLAMAPT | |
| SCHEMBL503642 | 0.74 | KMT2A (1.00) | KMT2APARP10POLBGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |