Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352089 | 0.88 | TP53 (0.49) | MEN1KMT2AALDH1A1KDM4EOPRK1 | |
| SCHEMBL6349137 | 0.87 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EOPRK1 | |
| SCHEMBL6359773 | 0.85 | MEN1 (0.64) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6350610 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTAKR1C4AKR1C3 | |
| SCHEMBL6834204 | 0.81 | KMT2A (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6358636 | 0.81 | PRMT1 (0.50) | MEN1KMT2AKDM4EMAPTAKR1C4 | |
| SCHEMBL6346641 | 0.80 | METAP2 (0.58) | MEN1KMT2AMAPTAKR1C4AKR1C3 | |
| SCHEMBL6352275 | 0.80 | AKR1C2 (0.53) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL9513479 | 0.79 | MAPT (0.80) | MEN1KMT2AMAPTAKR1C4AKR1C3 | |
| SCHEMBL17166275 | 0.79 | AKR1C2 (0.73) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MEN1 3274/4885KMT2A 3645/4885ALDH1A1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.