Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.44 |
| ▸ | CA9 | Q16790 | 14/20 | 0.44 |
| ▸ | CA1 | P00915 | 14/20 | 0.44 |
| ▸ | CA12 | O43570 | 13/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261507 | 0.74 | MAPK1 (0.33) | CA2CA9CA1CA12ALDH1A1 | |
| SCHEMBL27760686 | 0.74 | ENPP2 (0.36) | CA2CA9CA1CA12ALDH1A1 | |
| SCHEMBL28165369 | 0.73 | CHKA (0.39) | LMNATDP1 | |
| SCHEMBL2362320 | 0.73 | MAPT (0.35) | ALDH1A1KDM4ELMNA | |
| SCHEMBL27914491 | 0.71 | TSHR (0.40) | ALDH1A1 | |
| SCHEMBL2115712 | 0.70 | — | — | |
| SCHEMBL28249904 | 0.70 | KIF11 (0.37) | CA2CA9CA12TDP1 | |
| SCHEMBL4576927 | 0.68 | — | — | |
| SCHEMBL27039521 | 0.68 | ADRB2 (0.51) | ALDH1A1KDM4ELMNA | |
| SCHEMBL28178897 | 0.67 | CYP2A6 (0.40) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014368-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING INFLUENZA | VIROPHARMA INCORPORATED (US) | 2001-03-01 | — | — | WO | claimed |