SCHEMBL7973404

SCHEMBL7973404

CCS(=O)(=O)NC(=O)c1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.56
FLT4 P35916 1/20 0.56
KDR P35968 1/20 0.56
HPGD P15428 5/20 0.51
SMN1; SMN2 Q16637 7/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.46
POLB P06746 1/20 0.46
TYK2 P29597 1/20 0.46
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
F2R P25116 1/20 0.46
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
FFAR1 O14842 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983472 0.88 FLT1 (0.52) FLT1FLT4KDRHPGDSMN1; SMN2
SCHEMBL7991060 0.82 F2R (0.46) FLT1FLT4KDRHPGDGAA
SCHEMBL6654274 0.81 MYC (0.61) FLT1FLT4KDRHPGDSMN1; SMN2
SCHEMBL7973194 0.81 FLT1 (0.58) FLT1FLT4KDRHPGDSMN1; SMN2
SCHEMBL7974323 0.81 ALDH1A1 (0.53) HPGDSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL7987848 0.81 HPGD (0.61) HPGDSMN1; SMN2KMT2AGAANPC1
SCHEMBL7973486 0.78 LMNA (0.40) HPGDGAAF2R
SCHEMBL7973351 0.78 CTSD (0.63) HPGDSMN1; SMN2GAANPC1RAB9A
SCHEMBL9176782 0.77 FLT1 (0.63) FLT1FLT4KDRHPGDSMN1; SMN2
SCHEMBL653805 0.77 FLT1 (0.77) FLT1FLT4KDRHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed