Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973398 | 0.89 | KCNA5 (0.41) | LMNAGAACA9CA1CA2 | |
| SCHEMBL7986990 | 0.83 | MYC (0.53) | LMNAGAAKDM4EMYCTSHR | |
| SCHEMBL7991060 | 0.78 | F2R (0.46) | LMNAGAAKCNA5KDM4EMYC | |
| SCHEMBL10946343 | 0.78 | LMNA (0.43) | LMNAGAAITGB1ITGA4TSHR | |
| SCHEMBL7973404 | 0.78 | FLT1 (0.56) | GAAF2RHPGD | |
| SCHEMBL7223846 | 0.78 | L3MBTL1 (0.49) | LMNAGAACA9CA1ITGB1 | |
| SCHEMBL418095 | 0.78 | CTSD (0.53) | LMNAGAACA9CA1CA2 | |
| SCHEMBL7973194 | 0.77 | FLT1 (0.58) | LMNAF2RHPGD | |
| SCHEMBL7987848 | 0.77 | HPGD (0.61) | LMNAGAAKDM4EHPGD | |
| SCHEMBL7974323 | 0.77 | ALDH1A1 (0.53) | KDM4ETSHRHTTF2RHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |