SCHEMBL7973533

SCHEMBL7973533

O=C(O)CSc1cc(F)c2c(c1F)C1(OC2=O)c2cc(F)c(O)cc2Oc2c1cc(F)c(O)c2F

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3654597 0.79 ALDH1A1 (0.36) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL1942298 0.79 ALDH1A1 (0.36) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL7960246 0.70 THRB (0.43) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL1644389 0.70 HPGD (0.41) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL1940455 0.68 ALDH1A1 (0.54) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL3656500 0.68 HPGD (0.54) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL5269025 0.66 ALDH1A1 (0.40) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL3655952 0.66 HPGD (0.40) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL6543986 0.66 THRB (0.54) ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL31073961 0.66 ALDH1A1 (0.30) ALDH1A1CYP2C9HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed