Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973626 | 0.95 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2HTTGLAUBE2N | |
| SCHEMBL7988668 | 0.94 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2ADORA3ADORA2BHTT | |
| SCHEMBL7975240 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4ESMN1; SMN2HTT | |
| SCHEMBL7985360 | 0.90 | POLB (0.40) | SMN1; SMN2HTTGLAUBE2NL3MBTL1 | |
| SCHEMBL7991646 | 0.90 | SMN1; SMN2 (0.43) | KDM4ESMN1; SMN2HTTGLAUBE2N | |
| SCHEMBL7988551 | 0.90 | ADORA3 (0.43) | ALDH1A1HPGDKDM4ECXCR2ADORA3 | |
| SCHEMBL7991597 | 0.90 | PDE4B (0.39) | ALDH1A1HPGDSMN1; SMN2ADORA3HTT | |
| SCHEMBL7988781 | 0.90 | MET (0.43) | SMN1; SMN2HTTGLAUBE2NL3MBTL1 | |
| SCHEMBL7985336 | 0.89 | PIK3CA (0.42) | ALDH1A1HPGDCXCR2SMN1; SMN2ADORA3 | |
| SCHEMBL7991566 | 0.89 | ACP1 (0.43) | KDM4ESMN1; SMN2HTTGLAUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |