Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110350 | 0.82 | CYP11B1 (0.47) | TSHRKDM4EKDM5B | |
| SCHEMBL7529758 | 0.79 | CYP11B2 (0.51) | CYP1A2CYP2C9CYP2C19CYP2D6HPGD | |
| SCHEMBL29900474 | 0.77 | AOC1 (0.43) | MAPTGAATSHRKDM4ELMNA | |
| SCHEMBL6249306 | 0.77 | AOC1 (0.43) | MAPTGAATSHRKDM4ELMNA | |
| SCHEMBL11632014 | 0.76 | MEN1 (0.47) | MEN1MAPTKMT2ACYP3A4HPGD | |
| SCHEMBL5109030 | 0.75 | CYP11B1 (0.47) | TSHRKDM4EKDM5B | |
| SCHEMBL30851377 | 0.75 | CYP11B2 (0.54) | MAPTHPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL3820660 | 0.75 | RPS6KA3 (0.44) | MAPTHPGDALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL31303524 | 0.75 | AOC1 (0.45) | MAPTCYP2C9CYP2C19GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL21618217 | 0.75 | AOC1 (0.45) | MAPTCYP2C9CYP2C19GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |